Of particular importance for cell survival is the accurate, efficient and rapid duplication of the cellular genome. During the process of cell division everything within the cell must be duplicated in order to ensure the survival of the two resulting daughter cells. Most cells of the body fall into the latter category of cells. stem cells), others divide a specific number of times until cell death ( apoptosis) occurs, and still others divide a few times before entering a terminally differentiated or quiescent state. Some cells are continually dividing (e.g. Table of Mammalian Base Excision Repair EnzymesĪll cells undergo a division cycle during their life span.DNA Methylation Role in X Chromosome Inactivation.Mechanisms of X Chromosome Inactivation.X Chromosome Inactivation: Contributions from DNA Methylation.DNA Methylation: Role in Genomic Imprinting.Post-Replicative Modification of DNA: Cytidine Methylation.Telomere Replication: Implications for Aging and Disease.
Histone Modifications Regulating Chromatin Structure.DNA Demethylation: Removal of m5C (5mC).DNA Methylation: Formation of m5C (5mC).Nucleotide Modifications Regulating Chromatin Structure.
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